Gender Differences in the Management of Diabetic Patients with Hypertension and Chronic Ischemic Heart Disease

Vivencio Barrios1, *, Carlos Escobar2, Alberto Calderón3, Rocio Echarri4
1 Department of Cardiology, Hospital Ramón y Cajal, Madrid, Spain.
2 Department of Cardiology, Hospital Infanta Sofía, Madrid, Spain/
3 Primary care center Rosa Luxemburgo, Madrid, Spain.
4 Department of Nephrology, Hospital Infanta Sofía, Madrid, Spain.

© Barrios et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Cardiology, Hospital Ramón y Cajal, Ctra. De Colmenar km 9,100, 28034 Madrid, Spain. E-mails:,



To determine gender differences in cardiovascular risk factors control and clinical management in hypertensive diabetics with chronic ischemic heart disease. Research design and methods: CINHTIA was a cross-sectional and multicenter survey aimed to evaluate the clinical profile and management of hypertensive outpatients with chronic ischemic heart disease attended by cardiologists in Spanish clinical practice setting. The aim of the present work was to examine the gender differences in the control and treatment of cardiovascular risk factors in the subgroup of patients with diabetes. Adequate blood pressure (BP), LDL-cholesterol and diabetes control rates were defined according to ESH-ESC 2003, NCEP-ATP III and ADA-2005 guidelines, respectively


A total of 654 patients (42.4% women) were included for the present analysis. Women were older. Smoking, sedentary lifestyle and peripheral arterial disease were more frequent in men; left ventricular hypertrophy and heart failure in women. The total number of lipid lowering and antihypertensive agents were similar between genders, but with a trend to use more antidiabetic drugs in women. There was a tendency to a better BP control in men (21.5% vs 17.0%, p=0.09). LDL-cholesterol and diabetes were better controlled in men (34.6% vs 26.6%, p=0.04 and 29.7% vs 22.3%, p=0.025, respectively).


Diabetic women with hypertension and chronic ischemic heart disease exhibit lower control rates of cardiovascular risk factors.

Keywords: Hypertension, cardiologist setting, chronic ischemic heart disease.